{"product_id":"ghk-cu","title":"GHK-Cu","description":"\u003cdiv class=\"framer-17icvk9\" data-framer-name=\"Strong → Research Use Only.\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-dbnhlu\" data-styles-preset=\"UNBSR8FY_\" dir=\"auto\"\u003e\u003cem\u003e\u003cstrong\u003eResearch Use Only\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1j4pnbk\" data-framer-name=\"Strong → Research Use Only.\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-1ejfu8l\" data-styles-preset=\"joHcNFWNL\" dir=\"auto\"\u003eAll products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cdiv class=\"framer-6nrd7l\" data-framer-name=\"Overview\"\u003e\n\u003cdiv class=\"framer-e299os\" data-framer-name=\"Overview Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eGHK-Cu Overview\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-8mbkxy\" data-framer-name=\"Overview Body\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eGHK-Cu (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring copper-binding tripeptide studied for its role in molecular signaling, matrix remodeling, and pathway dynamics. In laboratory and preclinical models, GHK-Cu has been associated with modulation of gene expression, angiogenesis, and extracellular matrix activity, making it a valuable tool for research into experimental biology.\u003c\/p\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26155344\/\" rel=\"noopener\" target=\"_blank\"\u003ePickart L. et al. (2015).\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1ofh0jr\" data-framer-name=\"History\"\u003e\n\u003cdiv class=\"framer-7d5d5p\" data-framer-name=\"History Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eHistory\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1e0s2rr\" data-framer-name=\"History Body\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eGHK was first identified in the 1970s in biological plasma samples, where it was observed to decline with age. Subsequent research demonstrated that complexing GHK with copper enhanced its biological activity, particularly in processes related to extracellular matrix dynamics and molecular remodeling. Over the years, GHK-Cu has been extensively studied in models of epithelial biology, angiogenesis, and systemic regulation of gene expression.\u003c\/p\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29415049\/\" rel=\"noopener\" target=\"_blank\"\u003ePickart L., Margolina A. (2018). \u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-rpntv3\" data-border=\"true\" data-framer-name=\"Structure Section 1\"\u003e\n\u003cdiv class=\"framer-dg5g2i\" data-framer-name=\"Content\"\u003e\n\u003cdiv class=\"framer-1ccng99\" data-framer-name=\"Structure Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eGHK-Cu Structure\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-u3i1o2\" data-framer-name=\"Frame Above Picture\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"framer-hfrwpj\" data-framer-name=\"Structure Image\"\u003e\n\u003cdiv data-framer-background-image-wrapper=\"true\"\u003e\u003cimg decoding=\"auto\" loading=\"lazy\" width=\"1000\" height=\"1000\" sizes=\"calc(max((min(100vw, 980px) - 82px) \/ 1.95, 1px) - 48px)\" srcset=\"https:\/\/framerusercontent.com\/images\/C9oCdfrZSNEihUqClOp0KHlEPZQ.svg?scale-down-to=512\u0026amp;width=1000\u0026amp;height=1000 512w,https:\/\/framerusercontent.com\/images\/C9oCdfrZSNEihUqClOp0KHlEPZQ.svg?width=1000\u0026amp;height=1000 1000w\" src=\"https:\/\/framerusercontent.com\/images\/C9oCdfrZSNEihUqClOp0KHlEPZQ.svg?width=1000\u0026amp;height=1000\" alt=\"\"\u003e\u003c\/div\u003e\n\u003cdiv data-framer-background-image-wrapper=\"true\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-qqjc8t\" data-framer-name=\"Molecular Formula\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-1b1lbsc\" data-styles-preset=\"ptFoNsxY2\" dir=\"auto\"\u003e\u003cstrong\u003eMolecular Formula: C₁₄H₂₄CuN₆O₄\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eMolecular Weight: 340.9 g\/mol\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003ePubChem ID: 5311476\u003c\/strong\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1bb7rgf\" data-framer-name=\"Research Findings\"\u003e\n\u003cdiv class=\"framer-138hud5\" data-framer-name=\"Resarch Findings Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eResearch Findings\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1pwxkmo\" data-framer-name=\"Research Findings Body\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eGHK-Cu has been studied in structural, epithelial, and systemic models, with research highlighting its effects on collagen synthesis, extracellular matrix dynamics, and molecular remodeling. Studies also note its role in epithelial modeling, follicle signaling, and cytokine modulation in preclinical settings.\u003c\/p\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\u003cstrong class=\"framer-text\"\u003eKey Areas of Research:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul dir=\"auto\" class=\"framer-text\"\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eStructural: Collagen, matrix, connective signaling\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eEpithelial: Matrix dynamics, remodeling, follicle signaling\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eSystemic: Cytokine modulation, viability, pathway dynamics\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eTogether, these findings suggest broad experimental potential for GHK-Cu across structural, epithelial, and systemic pathways. By supporting collagen formation and molecular remodeling while modulating cytokine signaling, GHK-Cu provides a versatile platform for research into matrix dynamics, epithelial biology, and systemic resilience in laboratory settings.\u003c\/p\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/www.researchgate.net\/profile\/Jessica-Vasquez-Soltero\/publication\/275582600_GHK_Peptide_as_a_Natural_Modulator_of_Multiple_Cellular_Pathways_in_Skin_Regeneration\/links\/5540f9b90cf2322227314e70\/GHK-Peptide-as-a-Natural-Modulator-of-Multiple-Cellular-Pathways-in-Skin-Regeneration.pdf\" rel=\"noopener\" target=\"_blank\"\u003ePickart L. et al., 2015\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-14l2n57\" data-border=\"true\" data-framer-name=\"References\"\u003e\n\u003cdiv class=\"framer-15p1962\" data-framer-name=\"Content\"\u003e\n\u003cdiv class=\"framer-1ecatqh\" data-framer-name=\"Research Use Only\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eReferences\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1383kxn\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"framer-8qnss1\" data-framer-name=\"Research Use Only\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-pl80se\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40672369\/\" rel=\"noopener\" target=\"_blank\"\u003eMao S, Huang J, Li J, et al. Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms. \u003cem class=\"framer-text\"\u003eFront Pharmacol\u003c\/em\u003e. 2025;16:1551843. Published 2025 Jul 2. doi:10.3389\/fphar.2025.1551843\u003c\/a\u003e\u003c\/p\u003e\n\u003cp class=\"framer-text framer-styles-preset-pl80se\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28370978\/\" rel=\"noopener\" target=\"_blank\"\u003eWang X, Liu B, Xu Q, et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. \u003cem class=\"framer-text\"\u003eWound Repair Regen\u003c\/em\u003e. 2017;25(2):270-278. doi:10.1111\/wrr.12520\u003c\/a\u003e\u003c\/p\u003e\n\u003cp class=\"framer-text framer-styles-preset-pl80se\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35083444\/\" rel=\"noopener\" target=\"_blank\"\u003eDou Y, Lee A, Zhu L, Morton J, Ladiges W. The potential of GHK as an anti-aging peptide. \u003cem class=\"framer-text\"\u003eAging Pathobiol Ther\u003c\/em\u003e. 2020;2(1):58-61. doi:10.31491\/apt.2020.03.014\u003c\/a\u003e\u003c\/p\u003e\n\u003cp class=\"framer-text framer-styles-preset-pl80se\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29986520\/\" rel=\"noopener\" target=\"_blank\"\u003ePickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. \u003cem class=\"framer-text\"\u003eInt J Mol Sci\u003c\/em\u003e. 2018;19(7):1987. Published 2018 Jul 7. doi:10.3390\/ijms19071987\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Peptiders","offers":[{"title":"50mg \/ Single Vial","offer_id":44973283901526,"sku":null,"price":49.0,"currency_code":"USD","in_stock":true},{"title":"50mg \/ Pack of 10","offer_id":44973284917334,"sku":null,"price":439.0,"currency_code":"USD","in_stock":true},{"title":"100mg \/ Single Vial","offer_id":44973283934294,"sku":null,"price":89.0,"currency_code":"USD","in_stock":true},{"title":"100mg \/ Pack of 10","offer_id":44973284950102,"sku":null,"price":799.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/8787\/7206\/files\/GHK-Cu.avif?v=1781644679","url":"https:\/\/peptidersresearch.com\/products\/ghk-cu","provider":"Peptiders Researcher","version":"1.0","type":"link"}