{"product_id":"oxytocin","title":"Oxytocin","description":"\u003cdiv class=\"framer-17icvk9\" data-framer-name=\"Strong → Research Use Only.\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-dbnhlu\" data-styles-preset=\"UNBSR8FY_\" dir=\"auto\"\u003e\u003cem\u003e\u003cstrong\u003eResearch Use Only\u003c\/strong\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1j4pnbk\" data-framer-name=\"Strong → Research Use Only.\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-1ejfu8l\" data-styles-preset=\"joHcNFWNL\" dir=\"auto\"\u003eAll products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cdiv class=\"framer-6nrd7l\" data-framer-name=\"Overview\"\u003e\n\u003cdiv class=\"framer-e299os\" data-framer-name=\"Overview Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eOxytocin Overview\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-8mbkxy\" data-framer-name=\"Overview Body\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eOxytocin is a cyclic nonapeptide with a disulfide bridge between cysteine residues at positions 1 and 6, synthesized as a prohormone in hypothalamic magnocellular neurons and transported to the posterior pituitary for release. Through binding to its target receptor (OXTR), a G-protein-coupled receptor, it activates phospholipase C-mediated pathways leading to intracellular calcium release and protein kinase C activation. Research models examine oxytocin's effects on smooth muscle signaling dynamics, myoepithelial contraction modeling, CNS behavioral pathways, stress response signaling, and autonomic nervous system modulation in laboratory settings.\u003cbr class=\"framer-text\"\u003e\u003cbr class=\"framer-text\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11274341\/\" rel=\"noopener\" target=\"_blank\"\u003eLee et al. (2009). Gimpl \u0026amp; Fahrenholz (2001).\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1ofh0jr\" data-framer-name=\"History\"\u003e\n\u003cdiv class=\"framer-7d5d5p\" data-framer-name=\"History Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eHistory\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1e0s2rr\" data-framer-name=\"History Body\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eOxytocin was first isolated from the posterior pituitary gland by Henry Dale in 1906, who observed its smooth muscle signaling properties. The complete amino acid sequence was determined by Vincent du Vigneaud in 1953, and he successfully synthesized the peptide shortly thereafter, earning the Nobel Prize in Chemistry in 1955. This represented the first synthesis of a polypeptide hormone and established oxytocin as a foundational molecule in peptide biochemistry and neuroendocrinology.\u003cbr class=\"framer-text\"\u003e\u003cbr class=\"framer-text\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/ja01115a553\" rel=\"noopener\" target=\"_blank\"\u003eDu Vigneaud et al. (1953).\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-rpntv3\" data-border=\"true\" data-framer-name=\"Structure Section 1\"\u003e\n\u003cdiv class=\"framer-dg5g2i\" data-framer-name=\"Content\"\u003e\n\u003cdiv class=\"framer-1ccng99\" data-framer-name=\"Structure Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eOxytocin Structure\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-u3i1o2\" data-framer-name=\"Frame Above Picture\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"framer-hfrwpj\" data-framer-name=\"Structure Image\"\u003e\n\u003cdiv data-framer-background-image-wrapper=\"true\"\u003e\u003cimg decoding=\"auto\" loading=\"lazy\" width=\"1000\" height=\"644\" sizes=\"calc(max((min(100vw, 980px) - 82px) \/ 1.95, 1px) - 48px)\" srcset=\"https:\/\/framerusercontent.com\/images\/nbtdEXGlmHHCyV45CnhZSD9o694.png?scale-down-to=512\u0026amp;width=1000\u0026amp;height=644 512w,https:\/\/framerusercontent.com\/images\/nbtdEXGlmHHCyV45CnhZSD9o694.png?width=1000\u0026amp;height=644 1000w\" src=\"https:\/\/framerusercontent.com\/images\/nbtdEXGlmHHCyV45CnhZSD9o694.png?width=1000\u0026amp;height=644\" alt=\"\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-ay3afz\" data-framer-name=\"Frame Below Picture\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"framer-3wrgap\" data-framer-name=\"CAS #\" data-framer-component-type=\"RichTextContainer\"\u003e\u003c\/div\u003e\n\u003cdiv class=\"framer-qqjc8t\" data-framer-name=\"Molecular Formula\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-1b1lbsc\" data-styles-preset=\"ptFoNsxY2\" dir=\"auto\"\u003e\u003cstrong\u003eMolecular Formula: C₄₃H₆₆N₁₂O₁₂S₂\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eMolecular Weight: 1007.19 g\/mol\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003ePubChem ID: 43930\u003c\/strong\u003e2\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1bb7rgf\" data-framer-name=\"Research Findings\"\u003e\n\u003cdiv class=\"framer-138hud5\" data-framer-name=\"Resarch Findings Header\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eResearch Findings\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-1pwxkmo\" data-framer-name=\"Research Findings Body\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eOxytocin has been extensively studied in neuroendocrinology, behavioral neuroscience, and endocrine signaling research, with investigations focusing on receptor-mediated signaling, CNS behavioral pathways, autonomic function, and neuromodulation in various experimental models. Studies examine central and peripheral oxytocin system functions.\u003cbr class=\"framer-text\"\u003e\u003cbr class=\"framer-text\"\u003eKey Areas of Research:\u003c\/p\u003e\n\u003cul dir=\"auto\" class=\"framer-text\"\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eEndocrine: Smooth muscle signaling, contraction dynamics, secretory pathways\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eCNS: Behavioral pathways, affiliation modeling, recognition\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eNeuroendocrine: HPA axis modulation, stress signaling, autonomic dynamics\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-preset-tag=\"p\" class=\"framer-text framer-styles-preset-2if8ww\"\u003e\n\u003cp class=\"framer-text framer-styles-preset-2if8ww\"\u003eSignaling: Neurotransmitter modulation, synaptic plasticity, reward pathways\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-2if8ww\"\u003eThese findings demonstrate oxytocin's diverse actions across reproductive, social, and stress-regulatory systems. As both a peripheral hormone and central neuropeptide, oxytocin provides a research framework for examining neuroendocrine integration, social cognition mechanisms, and autonomic nervous system regulation in diverse experimental contexts. \u003cbr class=\"framer-text\"\u003e\u003cbr class=\"framer-text\"\u003eLee et al., Progress in Neurobiology, 2009\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-14l2n57\" data-border=\"true\" data-framer-name=\"References\"\u003e\n\u003cdiv class=\"framer-15p1962\" data-framer-name=\"Content\"\u003e\n\u003cdiv class=\"framer-1ecatqh\" data-framer-name=\"Research Use Only\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003ch2 class=\"framer-text framer-styles-preset-17n1ut5\" data-styles-preset=\"Ze7_hb2TJ\" dir=\"auto\"\u003eReferences\u003c\/h2\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"framer-8qnss1\" data-framer-name=\"Research Use Only\" data-framer-component-type=\"RichTextContainer\"\u003e\n\u003cp dir=\"auto\" class=\"framer-text framer-styles-preset-pl80se\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19482229\/\" rel=\"noopener\" target=\"_blank\"\u003eLee H.J. et al. (2009). Oxytocin: the great facilitator of life. Progress in Neurobiology, 88(2):127-151.\u003c\/a\u003e \u003cbr class=\"framer-text\"\u003e\u003cbr class=\"framer-text\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/11274341\/\" rel=\"noopener\" target=\"_blank\"\u003eGimpl G. \u0026amp; Fahrenholz F. (2001). The oxytocin receptor system: structure, function, and regulation. Physiological Reviews, 81(2):629-683. \u003c\/a\u003e\u003cbr class=\"framer-text\"\u003e\u003ca class=\"framer-text framer-styles-preset-dxoa8s\" href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/ja01115a553\" rel=\"noopener\" target=\"_blank\"\u003e\u003cbr class=\"framer-text\"\u003eDu Vigneaud V. et al. (1953). The synthesis of an octapeptide amide with the hormonal activity of oxytocin. Journal of the American Chemical Society, 75(19):4879-4880.\u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Peptiders","offers":[{"title":"5mg \/ Single Vial","offer_id":44973108822102,"sku":null,"price":49.0,"currency_code":"USD","in_stock":true},{"title":"5mg \/ Pack of 10","offer_id":44973108854870,"sku":null,"price":439.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/8787\/7206\/files\/Oxytocin.avif?v=1781651582","url":"https:\/\/peptidersresearch.com\/products\/oxytocin","provider":"Peptiders Researcher","version":"1.0","type":"link"}